Cellectis S.A. (CLLS) and Advaxis Inc. (NASDAQ:ADXS) Comparing side by side

As Biotechnology businesses, Cellectis S.A. (NASDAQ:CLLS) and Advaxis Inc. (NASDAQ:ADXS), are affected by compare. This especially applies to their dividends, analyst recommendations, profitability, risk, institutional ownership, earnings and valuation.

Valuation and Earnings

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Cellectis S.A. 21.43M 35.53 78.69M -2.11 0.00
Advaxis Inc. 23.70M 1.58 33.21M -1.33 0.00

We can see in table 1 the earnings per share (EPS), top-line revenue and valuation of Cellectis S.A. and Advaxis Inc.


Table 2 represents Cellectis S.A. (NASDAQ:CLLS) and Advaxis Inc. (NASDAQ:ADXS)’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Cellectis S.A. -367.20% -23% -18.8%
Advaxis Inc. -140.13% -187.2% -95%

Volatility & Risk

Cellectis S.A. is 74.00% more volatile than S&P 500 due to its 1.74 beta. Competitively, Advaxis Inc.’s 294.00% volatility makes it more volatile than S&P 500, because of the 3.94 beta.


The Current Ratio and Quick Ratio of Cellectis S.A. are 11.2 and 11.2 respectively. Its competitor Advaxis Inc.’s Current Ratio is 2.2 and its Quick Ratio is 2.2. Cellectis S.A. can pay off short and long-term obligations better than Advaxis Inc.

Analyst Recommendations

Cellectis S.A. and Advaxis Inc. Recommendations and Ratings are available on the next table.

Sell Ratings Hold Ratings Buy Ratings Rating Score
Cellectis S.A. 0 2 1 2.33
Advaxis Inc. 0 1 0 2.00

Cellectis S.A.’s consensus target price is $35.25, while its potential upside is 98.15%. Advaxis Inc. on the other hand boasts of a $0.4 consensus target price and a -11.50% potential downside. Based on the analysts view we can conclude, Cellectis S.A. is looking more favorable than Advaxis Inc.

Insider & Institutional Ownership

Roughly 29.4% of Cellectis S.A. shares are held by institutional investors while 23.9% of Advaxis Inc. are owned by institutional investors. Competitively, 0.3% are Advaxis Inc.’s share held by insiders.


Here are the Weekly, Monthly, Quarterly, Half Yearly, Yearly and YTD Performance of both pretenders.

Performance (W) Performance (M) Performance (Q) Performance (HY) Performance (Y) Performance (YTD)
Cellectis S.A. 12.66% 10.81% -10.39% -33.67% -37.98% 17.6%
Advaxis Inc. -9.95% -9.76% -24.57% -76.58% -81.81% 80%

For the past year Cellectis S.A.’s stock price has smaller growth than Advaxis Inc.

Cellectis S.A., a gene-editing company, develops and sells immuno-oncology products based on gene-edited T-cells that express chimeric antigen receptors to target and eradicate cancer in France. The company operates through two segments, Therapeutics and Plants. Its lead product candidate is UCART19, an allogeneic T-cell product candidate for the treatment of CD19 expressing hematologic malignancies, which develop in acute lymphoblastic leukemia (ALL) and CLL. The companyÂ’s products also comprise UCART123 for acute myeloid leukemia indications and blastic plasmacytoid dendritic cell neoplasm; UCARTCS1 for multiple myeloma (MM) indications; UCART22 for ALL; and UCART38 for T-cell ALL and MM. In addition, it focuses on applying its gene-editing technologies to develop new generation plant products in the field of agricultural biotechnology. The company has strategic alliances with Pfizer Inc. to generate CAR T-cells in the field of oncology; Les Laboratoires Servier SAS to develop and commercialize product candidates; The University of Texas MD Anderson Cancer Center to research and develop novel cellular immunotherapies for patients suffering from various liquid tumors; and Cornell University to accelerate the development of a targeted immunotherapy for patients with acute myeloid leukemia. Cellectis S.A. was founded in 1999 and is headquartered in Paris, France.

Advaxis, Inc., a clinical stage biotechnology company, focuses on the discovery, development, and commercialization of Lm-LLO cancer immunotherapies in the United States. Its lead product Axalimogene filolisbac, an Lm-LLO immunotherapy product candidate, which completed its Phase II study for the treatment of human papilloma virus associated cancers, including cervical, head and neck, and anal cancer. The company is also developing ADXS-PSA, an Lm-LLO immunotherapy product candidate, which is in Phase I/II clinical trials designed to target the prostate specific antigen associated with prostate cancer; and ADXS-HER2, an Lm-LLO immunotherapy product candidate that is in Phase Ib clinical trials used for the treatment of human epidermal growth factor receptor 2 expressing cancers, including human and canine osteosarcoma. It has clinical trial collaboration agreements with Merck & Co., Inc. for the Phase I/II dose-escalation and safety study of ADXS31-142; and MedImmune, LLC to initiate a Phase I/II clinical study in the United States to evaluate MEDI4736, an investigational anti-PD-L1 immune checkpoint inhibitor. The company also has a licensing agreement with Global BioPharma Inc.; co-development and commercialization agreement with Especificos Stendhal SA de CV; and collaboration agreement with Amgen Inc. for the development and commercialization of ADXS-NEO, a preclinical investigational cancer immunotherapy treatment that activates patientÂ’s immune system to respond against mutations or neoepitopes. Advaxis, Inc. was founded in 2002 and is based in Princeton, New Jersey.

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